Correlation of Body Weight with Plasma Atherogenic Index in Obese Rats Given Black Garlic
DOI:
https://doi.org/10.62872/p1bneq65Keywords:
black garlic, plasma atherogenic index, obesityAbstract
Obesity triggers changes in blood lipid profiles and increases the risk of atherosclerosis, one of which is measured by the plasma atherogenic index (IAP). Black garlic contains active compounds such as allicin and S-allylcysteine, which are known to have hypolipidemic effects. This study aims to determine the relationship between changes in body weight and IAP values in obese rat models given black garlic extract. This study was a pre-post test experiment with a control, using 28 male Sprague Dawley rats divided into 4 groups: negative control (normal diet), positive control (high-fat and fructose diet), treatment dose 1 (black garlic 1.6 ml/day), and treatment dose 2 (black garlic 0.8 ml/day). Measurements of body weight and triglyceride and HDL levels were carried out before and after the intervention. The results showed that administration of black garlic caused significant changes in body weight and IAP values (p<0.05), but the correlation between changes in body weight and IAP values was not significant (p>0.05). In conclusion, there was no significant relationship between changes in body weight and IAP values in obese mice given black garlic.
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Copyright (c) 2025 Prima Adelin, Relly Angelica Putriza, Haves Ashan, Dian Puspita, Rifkind Rifkind , Letvimona Letvimona (Author)
This work is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.
This work is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.
