Journal of Pharmacopoeia is an international peer-reviewed and open access journal established to invite scientists and educators around the world to exchange and disseminate theory and practice orientated pharmaceuticals. All submitted manuscripts will be reviewed by the editors and then evaluated by a minimum of two International Reviewers through a double-blind review process. This is to ensure the quality of manuscripts published in the journal. Journal title : Journal of Pharmacopoeia Initials : JP Frequency : 2 (Two) times a year (Maret,September) DOI : 10.62872 ISSN Online : 3047-4469 Editor in Chief : Andi Hardianti, S.KM., M.Kes Managing Editor : Harsudianto Silaen, S.Kep, Ns, M.Kep. Assistant Editor : Kori Puspita Ningsih, A.Md., S.KM., M.K.M Publisher : PT. Anagata Sembagi Education Accreditation : On Process
Study of Public Knowledge on the Use of Herbal Medicines and Their Interactions
The use of herbal medicines has increased significantly in the past two decades, particularly in developing countries like Indonesia. This phenomenon is largely influenced by the perception that herbal medicines are safer due to their natural nature, although public understanding of scientific aspects, such as dosage, drug interactions, and side effects, remains very limited. Various studies have shown that combinations of herbal and conventional medicines, such as ginkgo biloba with anticoagulants or St. John's wort with antidepressants, can cause dangerous pharmacological interactions, including toxicity and decreased therapeutic efficacy. The lack of formal health education and the dominance of information from social media and advertising exacerbate misinformation in the community. Furthermore, many health workers have not received training in herbal pharmacology, thus preventing them from providing optimal evidence-based education. Weak regulations on the distribution and labeling of herbal products also contribute to the risk of unsafe self-medication practices. This study used a literature review with a qualitative-descriptive approach to assess the level of public knowledge and the risks of herbal drug interactions. The results are expected to form the basis for the development of integrative educational and regulatory policies to improve public health literacy and ensure safer, more rational, and evidence-based use of herbal medicines.
Copyright (c) 2025 Loso Judijanto (Author) https://creativecommons.org/licenses/by-sa/4.0
The Role of Clinical Pharmacy in Preventing Complications of Metabolic Syndrome
Metabolic syndrome is a cluster of interacting metabolic risk factors, including central obesity, hypertension, insulin resistance, hyperglycemia, and atherogenic dyslipidemia, which significantly increase the risk of cardiovascular disease and type 2 diabetes mellitus. The prevalence of metabolic syndrome continues to increase globally due to changes in sedentary lifestyles and high-calorie consumption patterns, making it a public health issue with serious clinical, social, and economic impacts. The resulting complications, such as coronary heart disease, stroke, chronic kidney failure, and neuropathy, not only worsen patients' quality of life but also increase long-term healthcare costs. Therefore, preventing complications needs to be prioritized with strategies that integrate healthy lifestyle modifications, medical interventions, and rational pharmacotherapy. Clinical pharmacists play a strategic role in the management of metabolic syndrome through medication therapy management (MTM), patient education, drug interaction detection, and increased therapy adherence. Interdisciplinary collaboration between pharmacists, physicians, nurses, nutritionists, and psychologists strengthens the effectiveness of comprehensive, more personalized interventions. This study uses qualitative methods through a literature review to analyze the role of clinical pharmacists in preventing metabolic syndrome complications. The results show that integrating the role of clinical pharmacists into the healthcare team, supported by regulations, technology, and ongoing training, is key to reducing the risk of complications and improving people's quality of life.
Copyright (c) 2025 Annis Rahmawaty (Author) https://creativecommons.org/licenses/by-sa/4.0
Analysis of Bioactive Content in Indonesian Local Superfoods as a Preventative of Degenerative Diseases
Degenerative diseases such as diabetes, cancer, and heart disease pose a major challenge to modern public health. One potential preventative measure is the use of local Indonesian superfoods rich in bioactive compounds. This study aims to identify the main bioactive compounds in various local Indonesian superfoods and explore their potential in preventing degenerative diseases. The research method used was a qualitative one with a literature study approach obtained from scientific journals, research reports, and interviews with nutritionists and food experts. Data analysis was conducted through content analysis with categorization of bioactives and their relationship to disease prevention mechanisms. The results showed that local superfoods such as moringa, tempeh, purple sweet potato, turmeric, ginger, mangosteen, guava, and soursop contain important bioactives such as flavonoids, polyphenols, isoflavones, anthocyanins, curcumin, gingerol, and acetogenins. These compounds act as antioxidants, anti-inflammatories, immunomodulators, and protective agents for cells, thus having significant potential in preventing degenerative diseases. These findings confirm that local Indonesian superfoods have strategic value not only as functional foods, but also as part of preventive public health efforts and national food sovereignty.
Copyright (c) 2025 Elen Christ Tambunan (Author) https://creativecommons.org/licenses/by-sa/4.0
Sustainability in the Pharmaceutical Industry: Solutions to Reduce Environmental Impact in Drug Production
The increase in pharmaceutical waste is a global concern due to its impact on the environment and public health. Pharmaceutical waste comes from a variety of sources, including households, healthcare facilities, and the pharmaceutical industry. This research aims to analyze the solutions needed to reduce the environmental impact in drug production. This study uses the Systematic Literature Review (SLR) method using a database from scopus. There are three stages carried out in mapping the analysis of solutions needed to reduce environmental impact in drug production, namely 1) harvesting data, 2) screening data and 3) Data Analysis and Visualization. Based on this step, seven scopus articles were analyzed. Based on research with the SLR method that has been carried out, it can be concluded that the solution to reduce environmental impact in drug production is 1) The Use of Environmentally Friendly Raw Materials, 2) Optimization of the Production Process, 3) More Effective Treatment of Pharmaceutical Waste, 4) Increased Distribution and Packaging Efficiency, 5) Stricter Environmental Regulations and Policies, and 6) Public Education and Awareness. The implications of this research are aimed at researchers and the pharmaceutical industry being more sustainable
Copyright (c) 2025 Imam Jayanto (Author) https://creativecommons.org/licenses/by-sa/4.0
Responsibility in Pharmaceutical Practice: Aplication of Beyond Use Date for Compounded Preparations
BUD (beyond use date) is very important to maintain the quality, safety, and effectiveness of the drug after the package is opened or blended. The purpose of this study is to evaluate the implementation of BUD (beyond use date) in various pharmaceutical facilities. This study uses the Systematic Literature Review (SLR) method. This study uses a database from scopus. There are three stages carried out in mapping evaluated the application of BUD (beyond use date) in various pharmaceutical facilities, namely : 1) harvesting data, 2) data screening, 3) data analysis and visualization. From the results of data harvesting, 8 articles were published. Based on research with the SLR method that has been carried out, it can be concluded that penerapan Beyond Use Date (BUD) In pharmaceutical preparations, it is a critical aspect that affects the stability, effectiveness, and safety of the drug for patients. Previous studies have shown that adherence to medical standards has a significant impact on the success of therapy. Therefore, this study emphasizes the need for better standardization, increased pharmacist compliance, as well as further research on the impact of the implementation of BUD in clinical pharmacy. The implications of this study are addressed to the researchers and the pharmaceutical practice.
Copyright (c) 2025 Pratika Azzahra, Erza Genatrika (Author) https://creativecommons.org/licenses/by-sa/4.0
Pharmacy Education: Preparing Pharmacists for Global Challenges in the Digital Age
This study aims to examine the development of pharmacy education in the digital era, as well as to prepare pharmacists to face global challenges. The method used is the Systematic Literature Review (SLR), which is carried out by collecting, evaluating, and synthesizing previous research results comprehensively. The research process includes identifying literature through academic databases such as Scopus, PubMed, Google Scholar, and ScienceDirect, selecting studies based on inclusion and exclusion criteria, extracting data related to objectives, methods, results, and conclusions, synthesizing findings, and reporting research results. The results of the study indicate that pharmacy education needs to transform to prepare competent pharmacists in the digital era. Integration of technology into the curriculum such as e-learning, blended learning, augmented reality (AR), and virtual reality (VR) provides a more flexible learning experience. In addition, mastery of technology such as big data, artificial intelligence (AI), and pharmacy information systems is essential to support evidence-based decision making and efficiency of health services. The challenges faced include limited infrastructure, resistance to change, and the gap between the competencies taught and the digital skills needed in the world of work. Therefore, curriculum updates and training for pharmacists who are already working are very necessary to ensure pharmacists are prepared to face an increasingly digitalized profession
Copyright (c) 2025 Saeful Amin, Fadli Fadli, Adhisty Kharisma Justicia (Author) https://creativecommons.org/licenses/by-sa/4.0
Antibiotics And Bacterial Resistance: A Global Challenge That Needs To Be Addressed
This study aims to explore the global challenges faced in addressing bacterial resistance to antibiotics, which are now one of the most serious health threats in the world. This study was conducted through the Systematic Literature Review (SLR) method by searching scientific articles from various databases such as PubMed, Scopus, and Google Scholar using the keywords "antibiotic resistance", "global health", "treatment failure", and "resistance mechanisms". The articles analyzed are publications in the last 10 years, focusing on the causes of resistance, their impact on global health, and countermeasures that have been carried out. The results of the study show that antibiotic resistance is mainly caused by the inappropriate use of antibiotics in the medical and non-medical sectors, lack of distribution supervision, and lack of development of new antibiotics. To overcome this, a comprehensive approach is needed, including increasing public education and health workers, strengthening regulations, and developing alternative therapies such as phagotherapy and vaccines. Without proper treatment, antibiotic resistance can lead to infection treatment failure, increased mortality rates, and burden the global health system
Copyright (c) 2025 Sugiah Sugiah, Fadli Fadli, Fitria Hariati , Khrisna Agung Cendekiawan (Author) https://creativecommons.org/licenses/by-sa/4.0
Effectiveness of Antibiotic Use in the Prevention and Treatment of Respiratory Tract Infections
This study aims to analyze the effectiveness of the use of antibiotics in the prevention and treatment of respiratory tract infections. This study uses the Systematic Literature Review (SLR) method. There are three stages carried out in mapping the effectiveness of antibiotic use in the prevention and treatment of respiratory tract infections, namely: 1) harvesting data, 2) screening data, and 3) Data Analysis and Visualization. This study uses a database from Scopus with scientific journals as many as 9 articles from the range of 2021 to 2024. The effectiveness of antibiotic use in the prevention and treatment of respiratory tract infections is influenced by a variety of factors, including patient adherence, duration of therapy, and vaccine availability and use. Excessive or improper use of antibiotics can increase bacterial resistance, so more sustainable strategies, such as vaccination and stricter antibiotic use policies, are needed to improve the effectiveness of prevention and treatment of respiratory tract infections. The implications of this study are expected to be useful for future researchers and can be used in clinical applications
Copyright (c) 2025 Andika Alfiansyah, Fadli Fadli, Lutvi Anggraeni, Khrisna Agung Cendekiawan (Author) https://creativecommons.org/licenses/by-sa/4.0
Pharmacological Effects of Curcumin in Chronic Inflammatory Therapy
Herbal plants Herbal plants in Indonesia have an important role in traditional medicine and public health. The study aims to evaluate the effectiveness and mechanism of action of curcumin in chronic inflammatory therapy. This study employs the Systematic Literature Review (SLR) methodology.. This study uses a database from Scopus of 9 Scopus articles from the range of 2020 to 2025. There are three stages carried out in mapping the effectiveness and mechanism of action of curcumin in chronic inflammatory therapy, namely data harvesting, screening data and Data Analysis and Visualization. The results obtained are that curcumin is effective in chronic inflammatory therapy by inhibiting the main inflammatory pathways (NF-ƙB and JAK/STAT), has antioxidant effects, accelerates tissue regeneration, and functions as an immunomodulator. However, the limited bioavailability of curcumin presents a significant challenge in its application. Nanoformulation technology and its combination with compounds like CMPs can enhance its effectiveness in clinical therapy.The implications of this research are directed to researchers, the community and the government
Copyright (c) 2025 Muntasir Muntasir, Anggia Faradina, Tutik Wuryandari, Khrisna Agung Cendekiawan (Author) https://creativecommons.org/licenses/by-sa/4.0
Ethics and Responsibility in Pharmaceutical Practice: Facing Moral Dilemmas in the Modern Era
Pharmacy practice plays a crucial role in the modern healthcare system, providing access to safe and effective medicines for the public. However, in carrying out their profession, pharmacists are often faced with complex moral dilemmas. The modern era, with technological advances and commercial pressures, further complicates ethical decision-making. This article aims to examine ethical responsibilities in pharmacy practice and how pharmacists deal with conflicts of interest between economic gain and patient interests. Using a Systematic Literature Review (SLR) approach, this study identifies the main challenges faced by pharmacists in maintaining professional integrity while meeting regulatory demands and social expectations. The results suggest that pharmacists must adopt a balanced, value-based approach, where priority is given to patient welfare without neglecting the business aspects that are an integral part of healthcare. The discussion also explains the importance of developing ethical guidelines that are adaptive and relevant to the challenges of the digital era. The conclusion of this study is that a collaborative approach between government, professional organizations, and educational institutions can help create a stronger framework to support pharmacists in dealing with moral dilemmas in the workplace.
Copyright (c) 2024 Imam Jayanto, Untung Gunawan, Moh. Yaqya (Author) https://creativecommons.org/licenses/by-sa/4.0
Community Pharmacy: The Role of Strategy in Increasing Access and Quality of Health Services
This study aims to analyze the strategic role of community pharmacies in improving access to and quality of healthcare services. The research method used was qualitative with a descriptive approach. Data were collected through in-depth interviews with pharmacists, patients, and stakeholders, observations of pharmacy services, and documentation studies related to operational standards and policies. Data analysis was conducted using the Miles & Huberman model through data reduction, data presentation, and conclusion drawing. The results showed that the strategies implemented by community pharmacies include expanding operating hours, digitizing services, providing medication delivery services, improving pharmacist competency, and implementing pharmaceutical service standards. These strategies have had a positive impact on improving public access to pharmaceutical services and the quality of healthcare services. However, challenges remain, including limited human resources, technological constraints in certain regions, and suboptimal regulations. This study confirms that community pharmacies have a strategic role in supporting the primary healthcare system and need to be supported by more comprehensive policies.
strategies for access to health services
Copyright (c) 2025 Nikmah Nuur Rochmah, Norma Winata (Author) https://creativecommons.org/licenses/by-sa/4.0
Evidence-Based Pharmacy: Integration of Data and Research in the Development of more Effective and Safer Drugs
The main objective of this study was to collect, evaluate, and synthesize findings from relevant studies on the use of evidence-based data in drug development. The method used was a Qualitative Systematic Literature Review (SLR), which focused on understanding in-depth how the integration of data from clinical trials, big data, and laboratory studies can improve drug efficacy and safety. Through this approach, the study identified experiences, perceptions, and findings in the literature on drug development, and how this evidence supports decisions in drug selection and testing. The results showed that evidence-based pharmacy has great potential to improve the efficacy and safety of therapies by leveraging the integration of data from various sources and advanced analytical technologies. This approach can address key challenges in modern pharmacy, such as drug resistance and patient response variability, and result in more personalized and effective therapies. However, the implementation of evidence-based pharmacy requires support from various stakeholders, including academia, industry, and policy makers. Challenges such as data interoperability and privacy protection need to be addressed to ensure wider adoption. With a strategic and collaborative approach, evidence-based pharmacy can be the foundation for better precision medicine in the future, providing significant benefits to patients worldwide.
Copyright (c) 2024 Dadang Muhammad Hasyim, Liza Rastiti (Author) https://creativecommons.org/licenses/by-sa/4.0
Pharmaceutical involvement in Infectious Disease control: Strategies, Challenge and Solutions
This study aims to explore the role of the pharmaceutical sector in controlling infectious diseases, focusing on strategies, challenges, and solutions that can be implemented. The research method used is Systematic Literature Review (SLR) to collect and analyze data from related literature. Inclusion criteria include articles published in the last ten years, using English or Indonesian, and discussing pharmaceutical strategies in controlling infectious diseases. The literature search process was carried out through scientific databases such as PubMed, Scopus, and Google Scholar. The results of this study are Infectious disease control strategies involve the development of new vaccines and drugs, efficient drug distribution, and public education. The pharmaceutical sector plays an important role in creating medical solutions and implementing vaccination campaigns. The main challenge is antimicrobial resistance, which is caused by the unwise use of antibiotics. To overcome this challenge, public education, strict supervision in health facilities, and the development of new drugs are needed. The application of digital technology, such as AI-based applications, can also help monitor drug use and provide early warnings about the spread of disease. The role of pharmacists is vital in providing information and education about disease prevention, correct drug use, and the importance of vaccination. With innovative solutions such as the development of emergency pharmaceutical packages, the implementation of e-prescription, and technology-based training for pharmacists, it is hoped that the global health system can be more resilient in dealing with infectious disease outbreaks. Collaboration between the pharmaceutical sector, governments, and international organizations is essential in strengthening infectious disease control efforts and improving the readiness of the global health system.
Copyright (c) 2024 Norma Winata, Dadang Muhammad Hasyim, Brevmana Anugrah Primulyanto (Author) https://creativecommons.org/licenses/by-sa/4.0
Building a Bridge Between Research and Practice: Transforming the Pharmaceutical Industry in the digital Era
This study aims to describe the role of digital transformation in bridging research and practice in the pharmaceutical industry, while identifying emerging barriers and opportunities. The method used is qualitative research with a descriptive approach, through in-depth interviews, observations, and documentation studies of pharmaceutical industry stakeholders. The results show that digitalization through the use of artificial intelligence, big data analytics, blockchain, and telepharmacy can accelerate the translation of research findings into industrial practice. However, this transformation still faces obstacles such as limited human resources, high investment costs, and regulations that are not yet fully adaptive. This study emphasizes that collaboration between academia, industry, and regulators, supported by digital technology, is key to building a more efficient, innovative, and evidence-based pharmaceutical industry model in the digital era
Copyright (c) 2025 Loso Judijanto, Jacky Chin, Apt. Irfan Ahsani (Author) https://creativecommons.org/licenses/by-sa/4.0
Effectiveness of Soursop Leaf Extract in Reducing Glucose Levels in Diabetes Mellitus Patients: Literature Study
Alternative treatment for lowering sugar levels can be done through the use of herbal plants such as soursop leaves. This study aims to evaluate the effectiveness of soursop leaf extract (Annona muricata L.) in reducing blood glucose levels in Diabetes Mellitus (DM) patients. This research uses a literature study method, with data taken from scientific articles or journals within the last five years. Data was collected using the Google Scholar search engine with the keywords "diabetes mellitus," "soursop leaf extract," and "reducing sugar levels". Research shows that soursop leaf extract (Annona muricata L.) contains flavonoids, tannins, alkaloids, and saponins which are effective in lowering blood glucose levels through various mechanisms, including inhibiting sugar absorption, increasing glucose tolerance, stimulating insulin release, and regulating carbohydrate metabolism enzymes. The results of clinical and in silico trials support the effectiveness of this extract, making it a potential herbal treatment alternative amidst the current high costs of diabetes care. This research encourages the use of soursop leaves as a promising therapy and recommends further research to optimize its benefits.
Copyright (c) 2024 Elisa Issusilaningtyas, Nikmah Nuur Rochmah (Author) https://creativecommons.org/licenses/by-sa/4.0
Biofarmasetics and Pharmacokinetics Study Analysis of Paracetamol Excretion Through Urine and Saliva
The purpose of this study was to determine that Paracetamol, also known as acetaminophen, is a commonly used analgesic and antipyretic drug to relieve pain and reduce fever. The process of metabolism and elimination of paracetamol from the body is important to understand, especially in the context of the safe use of this drug. This study aims to analyze the biopharmaceutics and pharmacokinetics studies of paracetamol excretion through urine and saliva as important indicators in understanding the metabolic and elimination processes of this drug. Paracetamol is rapidly and efficiently absorbed through the gastrointestinal tract, reaches the highest concentration in plasma in a short time, and is dispersed throughout the body fluids. The metabolic process of paracetamol mainly occurs in the liver, through two main phases: oxidation and conjugation with glucuronic and sulfuric acids. Excretion of drugs and their metabolites can occur through urine and saliva, with the kidney as the main organ in the excretion process. Qualitative analytical methods were used in this study to identify paracetamol metabolite compounds in urine and saliva samples and to evaluate the metabolic pathways involved. Glucoronide, sulfate, and phenol conjugate assays were used to detect the presence of paracetamol metabolites in the samples. The assay results showed that urine was more effective in excreting paracetamol compared to saliva. In conclusion, this study provides a better understanding of the metabolic process and elimination of paracetamol from the human body through the analysis of biopharmaceutics and pharmacokinetics studies. These results are important for understanding the therapeutic effects and toxicity of paracetamol as well as for developing more effective and safe drug use management strategies.
Copyright (c) 2024 Journal of Pharmacopoeia https://creativecommons.org/licenses/by-sa/4.0
Nanoteknologi Farmasi Ziprasidone Nanocrystals By Wet Media Milling Followed By Spray Drying AndLyophilization: Formulation And Process Parameter Optimization
lyophilisation. The research methods used include the preparation of Ziprasidone nanosuspension using size reduction technique, optimisation of process parameters, formulation of media milling technique, and evaluation of the physical stability of the optimised nanosuspension. The results of this study are expected to provide a better understanding of the use of nanocrystals in improving the solubility and bioavailability of drugs with poor solubility such as Ziprasidone. In addition, this study is also expected to provide new insights into the use of spray drying and lyophilisation technologies to improve the physical stability of drug nanosuspensions. In conclusion, this study highlights the importance of using nanocrystals in improving the solubility and bioavailability of drugs with poor solubility such as Ziprasidone. Spray drying and lyophilisation methods have been shown to be effective in improving the physical stability of drug nanosuspensions. This research can serve as a foundation for the development of more effective drug formulations that can be used in wider clinical applications.
The Role of Traditional Medicines as Chemopreventive and Suppressive Agents in Cancer Treatment Deanova Insiratu
The purpose of this study was to determine the role of traditional medicine as a chemopreventive and suppressive agent in the treatment of Deanova Insiratu Cancer. This study is a qualitative study, this study will use a retrospective and prospective observational approach. Data will be collected from the medical records of patients who have used Deanova Insiratu previously, as well as from direct observation and interviews with individuals who are currently using or have experience with this traditional medicine. Research Results Cancer or malignant tumors can occur due to the growth of body tissue cells that proliferate abnormally. Cancer prevention can be done with healthy living habits and avoiding risk factors that can cause cancer. Cancer treatment can be done in 4 ways, namely by surgery, radiotherapy, immunotherapy and chemotherapy. Cancer screening can be done with mammography, ultrasonography (USG), and Magnetic Resonance Imaging (MRI). Natural ingredients that have effects as cancer prevention and help cancer treatment include Soursop leaves (Annona muricata), Celery leaves (Apium graveolans linn), Red Atai Spike leaves (Angiopteris ferox copel), Benalu Kepel (Dendrophthoe pentandra (L.) Miq.), and Tapak Dara leaves (Catharanthus roseus).
Assessment of Pediatric Skin Patient Satisfaction with Pharmacy Services at Basmalah Clinic Jambi
The purpose of this study is to evaluate the level of satisfaction of pediatric skin patients with the pharmaceutical services provided at the Basmalah Jambi Clinic. The clinic is known as a primary health care provider in Jambi city and has a pharmacy unit that provides medicines for patients. Methods The research conducted was descriptive with an observational approach. The observational method is a collection technique on research subjects. The qualitative method in the study of Pediatric Satisfaction Assessment of Pharmaceutical Services at the Basmalah Jambi Clinic refers to a research approach that focuses on an in-depth understanding of patients' experiences, perceptions, and views of the pharmaceutical services they receive at the clinic. The results of this study indicate that pharmaceutical services at the Basmalah Jambi Clinic have met the needs and expectations of pediatric skin patients in general. However, there are some areas that need to be improved to enhance service quality and ensure continued patient satisfaction in the future.
Use of Kaolin in the Pharmaceutical and Cosmetic Industries
Kaolin, a white clay mineral composed mainly of kaolinite with the chemical formula Al2O3.2SiO2.2H2O, has been a subject of interest since the days of medieval western literature. This interest increased especially after the advent of a more empirical approach to pharmacology, the establishment of pharmacopoeias, and developments in mineralogy, chemistry, as well as pharmaceutical technology. The use of kaolin in pharmaceutical (both topical and oral) and cosmetic applications has become important. Although it has long been recognized as a remedy in traditional medicine, the use of kaolin as an active ingredient for various diseases continues to be researched. Unfortunately, research focused on the use of kaolin in pharmaceuticals and cosmetics is still fairly limited. Therefore, this article aims to highlight the role and benefits of kaolin in both fields. Kaolin has been shown to have antibacterial, antiviral, and antidiarrheal properties when administered orally, as well as serve as a skin-protective agent when used topically. Aside from being an active ingredient, kaolin is also often used as an excipient in pharmaceutical formulations, acting as a filler, emulsifier, suspending agent, and crusher. In the cosmetic world, kaolin is often used as a sunscreen and to treat the skin. This article is organized based on a literature review of various articles and journals relevant to the topic discussed.