Oral Diseases in Pregnant Women and Low Birth Weight Risk: A Case-Control Study in Mantikulore Sub-District, Palu City, 2025

Authors

  • Sunarsih Sunarsih Mahasiswa Prodi Magister Kesehatan Masyarakat, Universitas Muhammadiyah Palu Author
  • Rajindra Rajindra Universitas Muhammadiyah Palu Sulawesi Tengah Author
  • Munawir Hi. Usman Fakultas Kesehatan Masyarakat Universitas Muhammadiyah Palu Sulawesi Tengah Author
  • Gusman Gusman Poltekkes Kemenkes Palu Author

DOI:

https://doi.org/10.62872/5rxwwf07

Keywords:

Pregnant Women, oral health, LBW, DMF-T, OHI-S, CPITN, stomatitis, case-control

Abstract

Low Birth Weight (LBW), defined as birth weight less than 2,500 grams, remains a significant public health problem in Indonesia, including Palu City. Oral diseases during pregnancy are proposed as contributing risk factors. This study aimed to analyze the relationship between oral diseases in pregnant women, dental caries, gingivitis, periodontitis, and stomatitis, with LBW incidence in Mantikulore Sub-District, Palu City, 2025. An observational analytic design with a case-control approach was employed. A total of 114 respondents were recruited (57 cases: mothers delivering LBW infants; 57 controls: mothers delivering normal-weight infants). Oral health examinations were conducted using the DMF-T index (caries), OHI-S index (oral hygiene/gingivitis), and CPITN index (periodontal status); stomatitis history was assessed via questionnaire. Data were analyzed using Chi-Square tests and multiple logistic regression. Results demonstrated significant associations: high DMF-T with LBW (OR=4.14; p=0.001), poor OHI-S with LBW (OR=9.06; p=0.000), severe CPITN with LBW (OR=6.57; p=0.000), and stomatitis with LBW (OR=24.06; p=0.000). Multivariate analysis identified stomatitis as the most dominant factor associated with LBW (OR=20.19; p=0.000), followed by poor OHI-S (OR=6.94; p=0.016). The model explained 67.5% of LBW variation. Oral health of pregnant women is significantly associated with LBW; oral health screening should be integrated into routine antenatal care.

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References

Achmad, M. H., Samad, R., Gunardi, I., Sukmana, B. I., Nurhayaty, N., & Setiawati, F. (2021). Oral health problems and treatment needs in pregnant women in Indonesia. Pesqui Bras Odontopediatria Clin Integr, 21, e0137.

Amin, et al. (2021). Association of maternal dental caries and low birth weight outcomes. Journal of Maternal Health, 15(2), 88–95.

Arbildo-Vega, H. I., et al. (2024). Effect of treating periodontal disease in pregnant women on pregnancy outcomes: Meta-analysis. PMC.

Barker, D. J. P. (2007). The origins of the developmental origins theory. Journal of Internal Medicine, 261(5), 412–417.

Castaño-Suárez, L., et al. (2024). Linking periodontitis to adverse pregnancy outcomes. Current Oral Health Reports.

Chen, X., et al. (2024). Maternal periodontitis may cause lower birth weight in offspring: Mendelian randomization evidence. Clinical Oral Investigations.

Cho, G. J., et al. (2020). Association between dental caries and adverse pregnancy outcomes. Scientific Reports.

Dinas Kesehatan Kota Palu. (2024). Profil Dinas Kesehatan Kota Palu Tahun 2024. Palu.

Dinas Kesehatan Sulawesi Tengah. (2024). Profil Kesehatan Provinsi Sulawesi Tengah Tahun 2024. Palu.

Gao, Y., Zhou, H., Wu, H., Li, J., & Sun, J. (2022). Maternal risk factors for low birth weight in China: A hospital-based case-control study. BMC Pregnancy and Childbirth, 22(1), 102.

Gonzalez, et al. (2024). Maternal oral hygiene and adverse birth outcomes. BMC Pregnancy and Childbirth, 24, 211.

Jang, H., et al. (2021). Oral microflora and pregnancy: A systematic review. Scientific Reports.

Jati, S. P., Widyastuti, E., & Prameswari, G. N. (2023). Maternal periodontal disease and risk of low birth weight: A case-control study in Yogyakarta, Indonesia. Indonesian Journal of Dental Research, 2(1), 15–22.

Kementerian Kesehatan RI. (2023). Data dan Informasi Profil Kesehatan Indonesia 2023. Jakarta.

Kementerian Kesehatan RI. (2022). Profil Kesehatan Indonesia Tahun 2021. Jakarta.

Kementerian Kesehatan RI. (2019). Riset Kesehatan Dasar (Riskesdas) 2018. Jakarta: Badan Litbangkes.

Miller, W. D. (1891). The human mouth as a focus of infection. Dental Cosmos.

Nannan, M., et al. (2022). Periodontal disease in pregnancy and adverse pregnancy outcomes. Frontiers in Medicine.

Offenbacher, S., Katz, V., Fertik, G., Collins, J., Boyd, D., Maynor, G., McKaig, R., & Beck, J. (1996). Periodontal infection as a possible risk factor for preterm low birth weight. Journal of Periodontology, 67(10 Suppl), 1103–1113.

Offenbacher, S., Boggess, K. A., Murtha, A. P., Jared, H. L., Lieff, S., McKaig, R. G., et al. (2006). Progressive periodontal disease and risk of very preterm delivery. Obstetrics & Gynecology, 107(1), 29–36.

Padilla-Cáceres, T., Arbildo-Vega, H. I., et al. (2023). Association between the risk of preterm birth and low birth weight with periodontal disease in pregnant women: An umbrella review. Dentistry Journal, 11(3), 74.

Parhi, L., Abed, J., Shhadeh, A., Yagel, S., Mandelboim, O., & Bachrach, G. (2022). Placental colonization by Fusobacterium nucleatum. Cell Reports, 38(12), 110537.

Pecci-Lloret, M. P., et al. (2024). Oral manifestations in pregnant women: A systematic review. Journal of Clinical Medicine.

Qiu, X., Lodha, A., Shah, P. S., Smith, G., Campbell, S., Lee, S. K., et al. (2023). Global, regional, and national burden of low birthweight and preterm birth: Systematic analysis of population-based data. Lancet Global Health, 11(3), e345–e357.

Rahman, M. M., Ali, M., Mahmud, M., & Rahman, A. (2021). Maternal factors associated with low birth weight in rural Bangladesh: A prospective cohort study. BMC Pregnancy and Childbirth, 21(1), 760.

Sachelarie, L., Iman, A. E. H., et al. (2024). Impact of hormones and lifestyle on oral health during pregnancy: A prospective observational study. Medicina.

Salama, M., et al. (2024). The impact of scaling and root planing combined with mouthwash on preterm and low birth weight: Meta-analysis of RCTs. BMC Pregnancy and Childbirth.

Setyawati, V., Nurdiati, D. S., & Hakimi, M. (2020). Environmental and maternal risk factors associated with low birth weight in Indonesia. Journal of Public Health Research, 9(3), 1866.

Sharma, et al. (2023). Oral disease during pregnancy and adverse birth outcomes. BMC Pregnancy and Childbirth, 23, 114.

Tefera, A. T., et al. (2025). Untreated dental caries and associated factors among pregnant women.

Tonetti, M. S., Greenwell, H., & Kornman, K. S. (2018). Staging and grading of periodontitis: Framework and proposal of a new classification and case definition. Journal of Periodontology / Journal of Clinical Periodontology.

Tsikouras, P., et al. (2024). The impact of periodontal disease on preterm birth and low birth weight. PMC Review.

Victora, C. G., Christian, P., Vidaletti, L. P., Gatica-Domínguez, G., Menon, P., & Black, R. E. (2021). Revisiting maternal and child undernutrition in low-income and middle-income countries. Lancet, 397(10282), 1388–1399.

World Health Organization. (2018). New global estimates on preterm birth and low birthweight. Geneva: WHO.

World Health Organization. (2022). Global oral health status report: Towards universal health coverage for oral health. Geneva: WHO.

World Health Organization. (2025). Oral health: Key facts. Geneva: WHO.

Wu, J., et al. (2024). Effects of different periodontal interventions on the risk of preterm birth and/or low birth weight: Systematic review and meta-analysis. Frontiers in Public Health.

Wulandari, et al. (2023). Stomatitis pada kehamilan dan luaran bayi baru lahir. Jurnal Gizi dan Kesehatan Reproduksi, 7(1), 12–20.

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Published

2026-05-30

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How to Cite

Oral Diseases in Pregnant Women and Low Birth Weight Risk: A Case-Control Study in Mantikulore Sub-District, Palu City, 2025. (2026). Journal of Public Health Indonesian, 3(1), 81-90. https://doi.org/10.62872/5rxwwf07

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